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Pseudobulbar affect is an emotional lability produced by degradation of the corticobulbar tracts in ALS that manifests as laughing, weeping, or yawning that is unrelated to a person’s real mood or cognitive state. Reference: https://medium.com/@alsdeanna0209/treatments-for-amyotrophic-lateral-sclerosis-als-symptoms-467e2be55d4b

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There is no cure for ALS, and no effective therapies exist to slow or stop the disease's development. The major symptoms of ALS are treated with two medications: Tiglutik and Rilutek (riluzole). Muscle cramps, excessive saliva and phlegm, uncontrollable weeping or laughing, discomfort, depression, sleep problems, and constipation may all be treated with other therapies and medicines. Refer

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